Chemical biology is of more recent provenance while biochemistry as a field goes back many decades by contrast. Because both fields deal with both chemistry and biology and overlap considerably, it can be difficult to set clearly defined boundaries between the two disciplines. Nonetheless, there is a difference in goals and emphasis.
Chemical Biology
Chemical biologists study the chemistry of life, like biochemists, but they seek ways to manipulate it using small molecules in difference. They too need strong knowledge of chemistry and biology, but they come primarily from a chemistry background and perspective. They focus to a greater degree on organic synthesis: how to design small molecules and synthesize them from smaller building blocks. Chemical biologists often work on the design of new drugs, although they may also work on experiments that explore the function of biological pathways using small molecular tools.
Biochemistry
Biological chemistry, or biochemistry, is the study of the chemical composition of living organisms at a cellular level. Included in this field of study are the structure of biological entities, the chemical properties of living organisms, and the changes in living cells caused by chemistry. It is a combination of life sciences and chemical sciences. Biochemists are especially interested in the structure and function of biological macromolecules such as proteins, lipids, carbohydrates and DNA; the pathways by which cells synthesize important molecules; and the molecular processes that enable cells to carry out their functions. Biochemists must have extensive knowledge of organic chemistry, although they come primarily from a biology background and perspective.
Differences
Although there is a considerable amount of overlap between the two disciplines, the emphasis in each is different. A biochemist is usually more ill-acquainted with the techniques used to synthesize new molecules, while a chemical biologist is usually more ill-acquainted with molecular biology tools such as micro-arrays and cloning. A biochemist wants to understand the chemistry of life, whereas a chemical biologist wants to design interventions to treat disease or ensure other desirable outcomes. At pharmaceutical and biotechnology companies, chemical biologists design new drug candidates while biochemists design assays, or test, to determine which candidates have an effect.
Education
Chemical biologists usually go on to take more courses in pharmacology, physical, inorganic and organic chemistry, and master organic synthesis(6-Chloro-2-picoline, also 2-Chloro-6-methylpyridine having CAS No. 18368-63-3, is particularly used as an intermediate in organic synthesis), while biochemists generally go on to take more courses in biochemistry and molecular biology. Both biochemistry and chemical biology majors take a core of courses in mathematics, general chemistry, cell biology, physics, organic chemistry and genetics. A biochemist will probably have more experience in molecular biology lab classes, while a chemical biologist will probably have more experience in organic chemistry lab classes.
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